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Assay Detail

CHEMBL814412

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of 12-HHT synthesis in bovine platelet suspension
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Bos taurus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

1-imidazolyl(alkyl)-substituted di- and tetrahydroquinolines and analogues: syntheses and evaluation of dual inhibitors of thromboxane A(2) synthase and aromatase.
Jacobs C, Frotscher M, Dannhardt G, Hartmann RW.
J Med Chem (2000) 43 : 1841 -1851
PubMed 10794700 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.76 6.76

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL293122 1 6.76

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL293122 IC50 = 173.0 nM 6.76