Assay Detail
Functional
CHEMBL815304
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Effective concentration (EC50) required to inhibit UT7/TPO Cell Proliferation
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Hydrazinonaphthalene and azonaphthalene thrombopoietin mimics are nonpeptidyl promoters of megakaryocytopoiesis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 7.60 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3144775 | — | — | 1 | 9.00 |
| CHEMBL3144661 | — | — | 1 | 7.40 |
| CHEMBL3144664 | — | — | 1 | 7.30 |
| CHEMBL3144784 | — | — | 1 | 7.30 |
| CHEMBL3144662 | — | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3144775 | — | EC50 | = | 1.0 | nM | 9.00 |
| CHEMBL3144661 | — | EC50 | = | 40.0 | nM | 7.40 |
| CHEMBL3144664 | — | EC50 | = | 50.0 | nM | 7.30 |
| CHEMBL3144784 | — | EC50 | = | 50.0 | nM | 7.30 |
| CHEMBL3144662 | — | EC50 | = | 100.0 | nM | 7.00 |