Assay Detail
Functional
CHEMBL815305
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration (EC50) required to inhibit UT7/TPO Cell Proliferation was determined.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Hydrazinonaphthalene and azonaphthalene thrombopoietin mimics are nonpeptidyl promoters of megakaryocytopoiesis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.59 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3144844 | — | — | 1 | 7.16 |
| CHEMBL3144789 | — | — | 1 | 6.30 |
| CHEMBL3144852 | — | — | 1 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3144844 | — | EC50 | = | 70.0 | nM | 7.16 |
| CHEMBL3144789 | — | EC50 | = | 500.0 | nM | 6.30 |
| CHEMBL3144852 | — | EC50 | = | 500.0 | nM | 6.30 |