Assay Detail
Binding
CHEMBL815442
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Inhibition of human V1A vasopressin receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
From hit to lead. Analyzing structure-profile relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.45 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL420500 | — | — | 1 | 5.70 |
| CHEMBL115444 | — | — | 1 | 5.65 |
| CHEMBL116463 | — | — | 1 | 5.44 |
| CHEMBL325674 | — | — | 1 | 5.29 |
| CHEMBL115076 | — | — | 1 | 5.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL420500 | — | IC50 | = | 2010.0 | nM | 5.70 |
| CHEMBL115444 | — | IC50 | = | 2220.0 | nM | 5.65 |
| CHEMBL116463 | — | IC50 | = | 3650.0 | nM | 5.44 |
| CHEMBL325674 | — | IC50 | = | 5160.0 | nM | 5.29 |
| CHEMBL115076 | — | IC50 | = | 6650.0 | nM | 5.18 |