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Assay Detail

CHEMBL815473

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity towards human trypsin
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Trypsin (CHEMBL2095204)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Synthesis and SAR of benzamidine factor Xa inhibitors containing a vicinally-substituted heterocyclic core.
Fevig JM, Pinto DJ, Han Q, Quan ML, Pruitt JR, Jacobson IC, Galemmo RA, Wang S, Orwat MJ, Bostrom LL, Knabb RM, Wong PC, Lam PYS, Wexler RR.
Bioorg Med Chem Lett (2001) 11 : 641 -645
PubMed 11266160 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.24 7.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL158219 1 7.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL158219 Ki = 58.0 nM 7.24