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Assay Detail

CHEMBL815829

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of cell growth against WIDR human gastrointestinal adenocarcinoma cell lines in vitro
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type WiDr
Confidence 1 — Organism
Curated By Intermediate

Target

WiDr (CHEMBL614647)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis of 5-chloro-5,8-dideaza analogues of folic acid and aminopterin targeted for colon adenocarcinoma.
Hynes JB, Kumar A, Tomazic A, Washtien WL.
J Med Chem (1987) 30 : 1515 -1519
PubMed 3612694 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.38 5.38

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL36739 1 5.38

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL36739 IC50 = 4200.0 nM 5.38