Assay Detail
Functional
CHEMBL816188
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for potency against human colon carcinoma WiDr cells in a sulforhodamine B assay.
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | WiDr |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
1,4-disubstituted anthracene antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.33 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL25336 | BISANTRENE | 3.0 | 1 | 6.10 |
| CHEMBL125332 | — | — | 1 | 5.85 |
| CHEMBL22696 | — | — | 1 | 5.80 |
| CHEMBL287188 | — | — | 1 | 5.40 |
| CHEMBL333690 | — | — | 1 | 5.35 |
| CHEMBL332153 | — | — | 1 | 4.82 |
| CHEMBL125698 | — | — | 1 | 4.77 |
| CHEMBL121864 | — | — | 1 | 4.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL25336 | BISANTRENE | IC50 | = | 790.0 | nM | 6.10 |
| CHEMBL125332 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL22696 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL287188 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL333690 | — | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL332153 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL125698 | — | IC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL121864 | — | IC50 | = | 26000.0 | nM | 4.58 |