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Assay Detail

CHEMBL816192

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In Vitro cell growth inhibitory activity of CNDAC against Human Colon Carcinoma WiDr 5*10e2 cells on 20- min exposure
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type WiDr
Confidence 1 — Organism
Curated By Intermediate

Target

WiDr (CHEMBL614647)
Type CELL-LINE
Organism Homo sapiens

Publication

Nucleosides and nucleotides. 141. Chemical stability of a new antitumor nucleoside, 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine in alkaline medium: formation of 2'-C-cyano-2'-deoxy-1-beta-D-ribo-pentofuranosylcytosine and its antitumor activity.
Azuma A, Hanaoka K, Kurihara A, Kobayashi T, Miyauchi S, Kamo N, Tanaka M, Sasaki T, Matsuda A.
J Med Chem (1995) 38 : 3391 -3397
PubMed 7650692 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.78 4.78

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL337450 TAS-109 2.0 1 4.78

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL337450 TAS-109 IC50 = 16500.0 nM 4.78