Assay Detail
Functional
CHEMBL816197
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro cytotoxicity causing 50% growth inhibition was determined against WiDr (human colon carcinoma) cell line
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | WiDr |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and in vitro cytotoxicity of novel long chain busulphan analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.60 | 4.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL169275 | — | — | 1 | 4.61 |
| CHEMBL169400 | — | — | 1 | 4.59 |
| CHEMBL820 | BUSULFAN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL169275 | — | IC50 | = | 24850.0 | nM | 4.61 |
| CHEMBL169400 | — | IC50 | = | 25590.0 | nM | 4.59 |
| CHEMBL820 | BUSULFAN | IC50 | > | 100000.0 | nM | - |