Assay Detail
Binding
CHEMBL816240
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Compound was evaluated for its inhibitory activity against VRS (valyl tRNA synthetase) from staphylococcus aureus WCUH29
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Staphylococcus aureus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Analogues of SB-203207 as inhibitors of tRNA synthetases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.99 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL74755 | — | — | 1 | 7.52 |
| CHEMBL74395 | — | — | 1 | 6.90 |
| CHEMBL421500 | — | — | 1 | 6.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL74755 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL74395 | — | IC50 | = | 126.0 | nM | 6.90 |
| CHEMBL421500 | — | IC50 | = | 290.0 | nM | 6.54 |