Assay Detail
Binding
CHEMBL816294
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Inhibitory concentration against recombinant UDP-N-Acetylmuramate/L-Alanine Ligase (MurC) enzyme
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Benzylidene rhodanines as novel inhibitors of UDP-N-acetylmuramate/L-alanine ligase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.69 | 4.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL350164 | — | — | 1 | 4.92 |
| CHEMBL159484 | — | — | 1 | 4.75 |
| CHEMBL161669 | — | — | 1 | 4.66 |
| CHEMBL159357 | — | — | 1 | 4.62 |
| CHEMBL444807 | — | — | 1 | 4.62 |
| CHEMBL162348 | — | — | 1 | 4.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL350164 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL159484 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL161669 | — | IC50 | = | 22000.0 | nM | 4.66 |
| CHEMBL159357 | — | IC50 | = | 24000.0 | nM | 4.62 |
| CHEMBL444807 | — | IC50 | = | 24000.0 | nM | 4.62 |
| CHEMBL162348 | — | IC50 | = | 27000.0 | nM | 4.57 |