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Assay Detail

CHEMBL816479

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Apparent binding affinity on human 5-alpha reductase isozyme
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Pharmacological options in the treatment of benign prostatic hyperplasia.
Kenny B, Ballard S, Blagg J, Fox D.
J Med Chem (1997) 40 : 1293 -1315
PubMed 9135028 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 10 7.30 8.15

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL278283 1 8.15
CHEMBL283217 1 8.15
CHEMBL24825 1 7.70
CHEMBL27862 1 7.70
CHEMBL24969 1 7.60
CHEMBL578029 1 7.52
CHEMBL25592 1 7.30
CHEMBL283546 1 6.23
CHEMBL24249 1 5.38
CHEMBL279017 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL278283 Ki = 7.0 nM 8.15
CHEMBL283217 Ki = 7.0 nM 8.15
CHEMBL24825 Ki = 20.0 nM 7.70
CHEMBL27862 Ki = 20.0 nM 7.70
CHEMBL24969 Ki = 25.0 nM 7.60
CHEMBL578029 Ki = 30.0 nM 7.52
CHEMBL25592 Ki = 50.0 nM 7.30
CHEMBL283546 Ki = 590.0 nM 6.23
CHEMBL24249 Ki = 4200.0 nM 5.38
CHEMBL279017 Ki > 5000.0 nM -