Assay Detail
Binding
CHEMBL816522
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against cognate Staphylococcus aureus threonyl tRNA synthetase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Staphylococcus aureus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Threonine--tRNA ligase 1, cytoplasmic (CHEMBL3391) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Aminoalkyl adenylate and aminoacyl sulfamate intermediate analogues differing greatly in affinity for their cognate Staphylococcus aureus aminoacyl tRNA synthetases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.82 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1163068 | — | — | 1 | 7.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1163068 | — | IC50 | = | 15.0 | nM | 7.82 |