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Assay Detail

CHEMBL816675

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Functional
Compound was evaluated for antagonistic activity towards Tachykinin receptor 2 at guinea pig trachea
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cavia porcellus
Tissue Trachea
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Substance-K receptor (CHEMBL2647)
Type SINGLE PROTEIN
Organism Cavia porcellus

Publication

Neuronorm is a potent and water soluble neurokinin A receptor antagonist.
Lombardi A, D'Agostino B, Filippelli A, Pedone C, Matera MG, Falciani M, De Rosa M, Rossi F, Pavone V.
Bioorg Med Chem Lett (1998) 8 : 1735 -1740
PubMed 9873425 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 7.63 7.63

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL334721 1 7.63

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL334721 Kd = 23.44 nM 7.63