Assay Detail
Binding
CHEMBL816865
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of c-Src tyrosine kinase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Proto-oncogene tyrosine-protein kinase Src (CHEMBL267) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Use of a pharmacophore model for the design of EGF-R tyrosine kinase inhibitors: 4-(phenylamino)pyrazolo[3,4-d]pyrimidines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.09 | 5.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL120069 | — | — | 1 | 5.09 |
| CHEMBL120319 | — | — | 1 | - |
| CHEMBL119977 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL120069 | — | IC50 | = | 8080.0 | nM | 5.09 |
| CHEMBL120319 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL119977 | — | IC50 | > | 10000.0 | nM | - |