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Assay Detail

CHEMBL816945

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Binding
Compound was tested for inhibitory activity against alpha-1,2-Fucosidase obtained from Arthrobacter oxidans
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Arthrobacter oxydans
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Tissue alpha-L-fucosidase (CHEMBL4176)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Chemoenzymatic synthesis of iminocyclitol derivatives: a useful library strategy for the development of selective fucosyltransfer enzymes inhibitors.
Wischnat R, Martin R, Takayama S, Wong CH.
Bioorg Med Chem Lett (1998) 8 : 3353 -3358
PubMed 9873733 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.40 8.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL114103 1 8.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL114103 IC50 = 4.0 nM 8.40