Assay Detail
Binding
CHEMBL816973
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for inhibitory activity against trypsin
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
1-Aminoisoquinoline as benzamidine isoster in the design and synthesis of orally active thrombin inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.77 | 6.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL51173 | — | — | 1 | 6.77 |
| CHEMBL329908 | — | — | 1 | - |
| CHEMBL159435 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL51173 | — | IC50 | = | 169.0 | nM | 6.77 |
| CHEMBL329908 | — | IC50 | = | 378000.0 | nM | - |
| CHEMBL159435 | — | IC50 | = | 255000.0 | nM | - |