Assay Detail
Binding
CHEMBL817134
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity against Trypsin
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Protease inhibitors: current status and future prospects.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 7.53 | 10.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL290376 | — | — | 1 | 10.35 |
| CHEMBL430526 | — | — | 1 | 9.34 |
| CHEMBL40854 | — | — | 1 | 9.15 |
| CHEMBL19902 | DX-9065A | — | 1 | 6.21 |
| CHEMBL364255 | — | — | 1 | 6.07 |
| CHEMBL310290 | — | — | 1 | 4.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL290376 | — | Ki | = | 0.045 | nM | 10.35 |
| CHEMBL430526 | — | Ki | = | 0.46 | nM | 9.34 |
| CHEMBL40854 | — | Ki | = | 0.7 | nM | 9.15 |
| CHEMBL19902 | DX-9065A | Ki | = | 620.0 | nM | 6.21 |
| CHEMBL364255 | — | Ki | = | 860.0 | nM | 6.07 |
| CHEMBL310290 | — | Ki | = | 84000.0 | nM | 4.08 |