Assay Detail
Functional
CHEMBL817368
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Compound was tested in vitro for inhibitory activity against 5-alpha reductase isozyme homogenated from transfected Namalwa
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Indole derivatives as a new class of steroid 5 alpha-reductase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.17 | 6.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL710 | FINASTERIDE | 4.0 | 1 | 6.24 |
| CHEMBL24470 | — | — | 1 | 4.10 |
| CHEMBL90085 | — | — | 1 | - |
| CHEMBL318512 | — | — | 1 | - |
| CHEMBL347059 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL710 | FINASTERIDE | IC50 | = | 580.0 | nM | 6.24 |
| CHEMBL24470 | — | IC50 | = | 78700.0 | nM | 4.10 |
| CHEMBL90085 | — | IC50 | = | 357000.0 | nM | - |
| CHEMBL318512 | — | IC50 | = | 215000.0 | nM | - |
| CHEMBL347059 | — | IC50 | = | 341000.0 | nM | - |