Assay Detail
Binding
CHEMBL817527
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Inhibition of Leishmanial tubulin assembly
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Leishmania donovani |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and antitubulin activity of N1- and N4-substituted 3,5-dinitro sulfanilamides against African trypanosomes and Leishmania.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.19 | 5.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL298564 | — | — | 1 | 5.24 |
| CHEMBL53153 | — | — | 1 | 5.17 |
| CHEMBL55225 | — | — | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL298564 | — | IC50 | = | 5800.0 | nM | 5.24 |
| CHEMBL53153 | — | IC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL55225 | — | IC50 | = | 6900.0 | nM | 5.16 |