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Assay Detail

CHEMBL818259

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested for inhibitory activity against bovine trypsin
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Trypsin (CHEMBL2095204)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Discovery of LB30057, a benzamidrazone-based selective oral thrombin inhibitor.
Oh YS, Yun M, Hwang SY, Hong S, Shin Y, Lee K, Yoon KH, Yoo YJ, Kim DS, Lee SH, Lee YH, Park HD, Lee CH, Lee SK, Kim S.
Bioorg Med Chem Lett (1998) 8 : 631 -634
PubMed 9871573 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.48 5.48

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL7962 1 5.48

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL7962 Ki = 3290.0 nM 5.48