Assay Detail
Binding
CHEMBL818399
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Inhibition of VEGF-receptor 2 (KDR)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Vascular endothelial growth factor receptor 2 (CHEMBL279) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Synthesis and kinase inhibitory activity of 3'-(S)-epi-K-252a.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.55 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL94678 | — | — | 1 | 7.72 |
| CHEMBL281948 | K-252A | — | 1 | 7.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL94678 | — | IC50 | = | 19.0 | nM | 7.72 |
| CHEMBL281948 | K-252A | IC50 | = | 43.0 | nM | 7.37 |