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Assay Detail

CHEMBL818779

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Functional
Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR4a
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Cell Type CHO
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Metabotropic glutamate receptor 4 (CHEMBL2736)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

(+)-4-phosphonophenylglycine (PPG) a new group III selective metabotropic glutamate receptor agonist.
Gasparini F, Inderbitzin W, Francotte E, Lecis G, Richert P, Dragic Z, Kuhn R, Flor PJ.
Bioorg Med Chem Lett (2000) 10 : 1241 -1244
PubMed 10866390 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.50 5.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL277475 1 5.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL277475 EC50 = 3200.0 nM 5.50