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Assay Detail

CHEMBL818833

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement from vitamin D receptor in chick intestine: 50% displacement
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Gallus gallus
Tissue Intestine
Confidence 9 — Direct single protein target
Curated By Expert

Target

Vitamin D3 receptor (CHEMBL2353)
Type SINGLE PROTEIN
Organism Gallus gallus

Publication

Synthesis and biological evaluation of MC 1357, a new 20-epi-23-oxa-1,25-dihydroxy-vitamin D3 analogue with potent non-classical effects
Calverley MJ, Binderup L
Bioorg Med Chem Lett (1993) 3 : 1845 -1848
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 10.60 10.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL846 CALCITRIOL 4.0 1 10.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL846 CALCITRIOL Ki = 0.025 nM 10.60