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Assay Detail

CHEMBL818859

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Affinity for purified activated GPIIb/IIIa fibrinogen receptor by ELISA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 7 — Homologous single protein target
Curated By Autocuration

Target

Integrin alpha-IIb/beta-3 (CHEMBL2093869)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

2-Acylimino-3H-thiazoline derivatives: a novel template for platelet GPIIb/IIIa receptor antagonists.
Manaka A, Sato M, Aoki M, Tanaka M, Ikeda T, Toda Y, Yamane Y, Nakaike S.
Bioorg Med Chem Lett (2001) 11 : 1031 -1035
PubMed 11327582 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 10.33 10.33

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL8572 1 10.33

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL8572 Ki = 0.0465 nM 10.33