Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL819025

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Tested in vitro for effective concentration required for stimulation of phospholipase C (PLC) against [3H]inositol labeled Turkey Erythrocyte P2Y purinoceptor 1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Meleagris gallopavo
Confidence 1 — Organism
Curated By Intermediate

Target

Meleagris gallopavo (CHEMBL613110)
Type ORGANISM
Organism Meleagris gallopavo

Publication

Acyclic analogues of deoxyadenosine 3',5'-bisphosphates as P2Y(1) receptor antagonists.
Kim YC, Gallo-Rodriguez C, Jang SY, Nandanan E, Adams M, Harden TK, Boyer JL, Jacobson KA.
J Med Chem (2000) 43 : 746 -755
PubMed 10691699 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 5.17 5.20

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1230817 1 5.20
CHEMBL165225 1 5.14

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1230817 EC50 = 6290.0 nM 5.20
CHEMBL165225 EC50 = 7210.0 nM 5.14