Assay Detail
Binding
CHEMBL819103
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Competitive inhibition against rat cytoplasmic thymidine kinase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Species- or isozyme-specific enzyme inhibitors. 5. Differential effects of thymidine substituents on affinity for rat thymidine kinase isozymes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 4.68 | 4.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3143486 | — | — | 1 | 4.92 |
| CHEMBL3143685 | — | — | 1 | 4.44 |
| CHEMBL3143485 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3143486 | — | Ki | = | 12000.0 | nM | 4.92 |
| CHEMBL3143685 | — | Ki | = | 36000.0 | nM | 4.44 |
| CHEMBL3143485 | — | Ki | = | 320000.0 | nM | - |