Assay Detail
Binding
CHEMBL819309
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of phosphodiesterase from bovine aorta with 1 uM cGMP calcium (10 uM) and calmodulin (15 nM)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Inhibition of cyclic adenosine-3',5'-monophosphate phosphodiesterase from vascular smooth muscle by rolipram analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.89 | 4.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL285913 | TREQUINSIN | 2.0 | 1 | 4.89 |
| CHEMBL284845 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL285913 | TREQUINSIN | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL284845 | — | IC50 | = | 230000.0 | nM | - |