Assay Detail
Binding
CHEMBL819372
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of AVP mediated activation of human vasopressin V1a receptor expressed in HEK293 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Bridged bicyclic vasopressin receptor antagonists with V(2)-selective or dual V(1a)/V(2) activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.85 | 7.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL430841 | — | — | 1 | 7.64 |
| CHEMBL106229 | — | — | 1 | 6.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL430841 | — | Ki | = | 23.0 | nM | 7.64 |
| CHEMBL106229 | — | Ki | = | 890.0 | nM | 6.05 |