Assay Detail
Functional
CHEMBL819561
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Antiviral activity against HSV-1 strain F in Vero cells on day 2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Chlorocebus sabaeus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological properties of 5-o-carboranyl-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.92 | 4.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3142561 | — | — | 1 | 4.92 |
| CHEMBL129 | ZIDOVUDINE | 4.0 | 1 | - |
| CHEMBL3142559 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3142561 | — | EC50 | = | 11900.0 | nM | 4.92 |
| CHEMBL129 | ZIDOVUDINE | EC50 | > | 50000.0 | nM | - |
| CHEMBL3142559 | — | EC50 | > | 10000.0 | nM | - |