Assay Detail
Binding
CHEMBL819610
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Compound was tested in vivo for its ability to inhibit mouse kidney cytidine deaminase (CDA)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Furanose-pyranose isomerization of reduced pyrimidine and cyclic urea ribosides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.72 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2311128 | TETRAHYDROURIDINE | 2.0 | 1 | 6.82 |
| CHEMBL2367576 | — | — | 1 | 6.52 |
| CHEMBL2367575 | — | — | 1 | 5.40 |
| CHEMBL4524098 | — | — | 1 | 5.18 |
| CHEMBL308774 | — | — | 1 | 4.70 |
| CHEMBL308139 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2311128 | TETRAHYDROURIDINE | Ki | = | 150.0 | nM | 6.82 |
| CHEMBL2367576 | — | Ki | = | 300.0 | nM | 6.52 |
| CHEMBL2367575 | — | Ki | = | 4000.0 | nM | 5.40 |
| CHEMBL4524098 | — | Ki | = | 6600.0 | nM | 5.18 |
| CHEMBL308774 | — | Ki | = | 20000.0 | nM | 4.70 |
| CHEMBL308139 | — | Ki | > | 50000.0 | nM | - |