Assay Detail
Functional
CHEMBL819657
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound tested against WiDr colon carcinoma (resistant) in the sulforhodamine B assay.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | WiDr |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
6- and 7-substituted 2-[2'-(dimethylamino)ethyl]-1,2-dihydro-3H-dibenz[de,h] isoquinoline-1,3-diones: synthesis, nucleophilic displacements, antitumor activity, and quantitative structure-activity relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.50 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL40515 | — | — | 1 | 8.00 |
| CHEMBL40716 | — | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL40515 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL40716 | — | IC50 | = | 100.0 | nM | 7.00 |