Assay Detail
Binding
CHEMBL819682
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for the concentration to inhibit 50% of tubulin polymerization.
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Antineoplastic agents. 379. Synthesis of phenstatin phosphate.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.49 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL67 | COMBRETASTATIN A4 | -1.0 | 1 | 5.92 |
| CHEMBL47426 | — | — | 1 | 5.89 |
| CHEMBL297299 | — | — | 1 | 5.46 |
| CHEMBL44574 | — | — | 1 | 4.68 |
| CHEMBL289351 | FOSBRETABULIN DISODIUM | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL67 | COMBRETASTATIN A4 | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL47426 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL297299 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL44574 | — | IC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL289351 | FOSBRETABULIN DISODIUM | IC50 | > | 80000.0 | nM | - |