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Assay Detail

CHEMBL819880

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Binding
Compound was tested for inhibitory activity against alpha-Fucosidase obtained from Bovine epididymis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Tissue alpha-L-fucosidase (CHEMBL4176)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Chemoenzymatic synthesis of iminocyclitol derivatives: a useful library strategy for the development of selective fucosyltransfer enzymes inhibitors.
Wischnat R, Martin R, Takayama S, Wong CH.
Bioorg Med Chem Lett (1998) 8 : 3353 -3358
PubMed 9873733 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 7.91 8.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL114103 1 8.10
CHEMBL539176 1 7.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL114103 Ki = 8.0 nM 8.10
CHEMBL539176 Ki = 19.0 nM 7.72