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Assay Detail

CHEMBL820115

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Agonistic activity was determined by measuring the compound's ability to induce superoxide production(as measured by reduction of cytochrome C) using human neutrophils
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

N-terminus urea-substituted chemotactic peptides: new potent agonists and antagonists toward the neutrophil fMLF receptor.
Higgins JD, Bridger GJ, Derian CK, Beblavy MJ, Hernandez PE, Gaul FE, Abrams MJ, Pike MC, Solomon HF.
J Med Chem (1996) 39 : 1013 -1015
PubMed 8676333 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.40 6.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL266089 1 6.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL266089 EC50 = 400.0 nM 6.40