Assay Detail
Binding
CHEMBL820185
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity towards cRAR-beta-2 receptor by displacing 1.1 nM 3[H]-9-cis-RA
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Synthesis and receptor binding affinity of conformationally restricted retinoic acid analogues
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.30 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL275311 | — | — | 1 | 9.30 |
| CHEMBL705 | ALITRETINOIN | 4.0 | 1 | 9.30 |
| CHEMBL1023 | BEXAROTENE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL275311 | — | Ki | = | 0.5 | nM | 9.30 |
| CHEMBL705 | ALITRETINOIN | Ki | = | 0.5 | nM | 9.30 |
| CHEMBL1023 | BEXAROTENE | Ki | > | 800.0 | nM | - |