Assay Detail
Binding
CHEMBL820187
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Binding affinity towards cRARbeta2 receptor by displacing 0.82 nM 3[H]all-trans-RA
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Synthesis and receptor binding affinity of conformationally restricted retinoic acid analogues
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.63 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL38 | TRETINOIN | 4.0 | 1 | 9.30 |
| CHEMBL74331 | — | — | 1 | 7.96 |
| CHEMBL73973 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL38 | TRETINOIN | Ki | = | 0.5 | nM | 9.30 |
| CHEMBL74331 | — | Ki | = | 11.0 | nM | 7.96 |
| CHEMBL73973 | — | Ki | > | 1100.0 | nM | - |