Assay Detail
Functional
CHEMBL820794
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory activity against Wt-MCF7 human breast cell line
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, and evaluation of novel boronic-chalcone derivatives as antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 13 | 5.06 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL440145 | — | — | 1 | 5.30 |
| CHEMBL93371 | — | — | 1 | 5.26 |
| CHEMBL96269 | — | — | 1 | 5.22 |
| CHEMBL319204 | — | — | 1 | 5.16 |
| CHEMBL94710 | — | — | 1 | 5.16 |
| CHEMBL96702 | — | — | 1 | 5.11 |
| CHEMBL93446 | — | — | 1 | 5.07 |
| CHEMBL328253 | — | — | 1 | 5.05 |
| CHEMBL94637 | — | — | 1 | 5.05 |
| CHEMBL96581 | — | — | 1 | 5.02 |
| CHEMBL95090 | — | — | 1 | 4.89 |
| CHEMBL96817 | — | — | 1 | 4.82 |
| CHEMBL94639 | — | — | 1 | 4.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL440145 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL93371 | — | IC50 | = | 5500.0 | nM | 5.26 |
| CHEMBL96269 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL319204 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL94710 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL96702 | — | IC50 | = | 7800.0 | nM | 5.11 |
| CHEMBL93446 | — | IC50 | = | 8500.0 | nM | 5.07 |
| CHEMBL328253 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL94637 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL96581 | — | IC50 | = | 9500.0 | nM | 5.02 |
| CHEMBL95090 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL96817 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL94639 | — | IC50 | = | 19000.0 | nM | 4.72 |