Assay Detail
Binding
CHEMBL821359
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Binding to [125I]- fibrinogen by washed platelet fibrinogen receptor
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
2-Acylimino-3H-thiazoline derivatives: a novel template for platelet GPIIb/IIIa receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.47 | 8.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8277 | — | — | 1 | 8.20 |
| CHEMBL8572 | — | — | 1 | 7.95 |
| CHEMBL268859 | — | — | 1 | 7.29 |
| CHEMBL8187 | — | — | 1 | 7.22 |
| CHEMBL267528 | — | — | 1 | 7.17 |
| CHEMBL8283 | — | — | 1 | 6.98 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8277 | — | IC50 | = | 6.26 | nM | 8.20 |
| CHEMBL8572 | — | IC50 | = | 11.3 | nM | 7.95 |
| CHEMBL268859 | — | IC50 | = | 51.8 | nM | 7.29 |
| CHEMBL8187 | — | IC50 | = | 60.5 | nM | 7.22 |
| CHEMBL267528 | — | IC50 | = | 67.9 | nM | 7.17 |
| CHEMBL8283 | — | IC50 | = | 105.0 | nM | 6.98 |