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Assay Detail

CHEMBL821487

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Concentration required to inhibit mGlu receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis and preliminary evaluation of (S)-2-(4'-carboxycubyl)glycine, a new selective mGluR1 antagonist.
Pellicciari R, Costantino G, Giovagnoni E, Mattoli L, Brabet I, Pin JP.
Bioorg Med Chem Lett (1998) 8 : 1569 -1574
PubMed 9873392 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.83 5.83

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2021372 1 5.83

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2021372 EC50 = 1480.0 nM 5.83