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Assay Detail

CHEMBL821959

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro inhibition of ADP (5 uM) induced platelet aggregation of mouse platelet rich plasma
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Tissue Plasma
Confidence 6 — Multiple protein complex / RNA
Curated By Autocuration

Target

Integrin alpha-IIb/beta-3 (CHEMBL2093869)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

2-Acylimino-3H-thiazoline derivatives: a novel template for platelet GPIIb/IIIa receptor antagonists.
Manaka A, Sato M, Aoki M, Tanaka M, Ikeda T, Toda Y, Yamane Y, Nakaike S.
Bioorg Med Chem Lett (2001) 11 : 1031 -1035
PubMed 11327582 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.44 7.44

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL8572 1 7.44

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL8572 IC50 = 36.6 nM 7.44