Assay Detail
Binding
CHEMBL822096
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Inhibitory activity against porcine pancreatic trypsin (TRP)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Symmetrical anhydride-type serine protease inhibitors: structure-activity relationship studies of human chymase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.53 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL108540 | — | — | 1 | 6.52 |
| CHEMBL134816 | — | — | 1 | 5.75 |
| CHEMBL338962 | — | — | 1 | 5.09 |
| CHEMBL336964 | — | — | 1 | 4.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL108540 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL134816 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL338962 | — | IC50 | = | 8200.0 | nM | 5.09 |
| CHEMBL336964 | — | IC50 | = | 18000.0 | nM | 4.75 |