Assay Detail
Binding
CHEMBL822540
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Competitive Inhibition constant on yeast alpha Glucosidase at pH 7.0
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological activity of C-6 modified derivatives of the glucosidase inhibitor 1-deoxynojirimycin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 4.51 | 4.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL307429 | DUVOGLUSTAT | 2.0 | 1 | 4.68 |
| CHEMBL111326 | — | — | 1 | 4.33 |
| CHEMBL108656 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL307429 | DUVOGLUSTAT | Ki | = | 21000.0 | nM | 4.68 |
| CHEMBL111326 | — | Ki | = | 47000.0 | nM | 4.33 |
| CHEMBL108656 | — | Ki | = | 2000000.0 | nM | - |