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Assay Detail

CHEMBL823371

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Tested in vitro against HSV 2 G strain in vero cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism herpes simplex virus
Cell Type Vero
Confidence 1 — Organism
Curated By Intermediate

Target

Human alphaherpesvirus 2 (CHEMBL370)
Type ORGANISM
Organism Human alphaherpesvirus 2

Publication

Synthesis and antiviral activity of 2'-substituted 9-[2-(phosphonomethoxy)ethyl]guanine analogues.
Yu KL, Bronson JJ, Yang H, Patick A, Alam M, Brankovan V, Datema R, Hitchcock MJ, Martin JC.
J Med Chem (1993) 36 : 2726 -2738
PubMed 8410987 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.00 4.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL419692 1 4.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL419692 IC50 = 99000.0 nM 4.00