Assay Detail
Functional
CHEMBL823717
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Inhibition of c-erb B-2/HER2/neu receptor
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Non-amine based analogues of lavendustin A as protein-tyrosine kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.60 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL103586 | — | — | 1 | 6.70 |
| CHEMBL102362 | — | — | 1 | 6.22 |
| CHEMBL319620 | LAVENDUSTIN C | — | 1 | 6.05 |
| CHEMBL103860 | — | — | 1 | 5.40 |
| CHEMBL103552 | LAVENDUSTIN A | — | 1 | 5.05 |
| CHEMBL316764 | — | — | 1 | 4.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL103586 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL102362 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL319620 | LAVENDUSTIN C | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL103860 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL103552 | LAVENDUSTIN A | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL316764 | — | IC50 | = | 70000.0 | nM | 4.16 |