Assay Detail
Binding
CHEMBL823888
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive Inhibition constant on almonds beta Glucosidase at pH 5.0
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Prunus dulcis |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological activity of C-6 modified derivatives of the glucosidase inhibitor 1-deoxynojirimycin.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.82 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL421040 | — | — | 1 | 5.82 |
| CHEMBL324632 | — | — | 1 | - |
| CHEMBL108656 | — | — | 1 | - |
| CHEMBL307429 | DUVOGLUSTAT | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL421040 | — | Ki | = | 1500.0 | nM | 5.82 |
| CHEMBL324632 | — | Ki | = | 780000.0 | nM | - |
| CHEMBL108656 | — | Ki | = | 630000.0 | nM | - |
| CHEMBL307429 | DUVOGLUSTAT | Ki | = | 300000.0 | nM | - |