Assay Detail
Functional
CHEMBL824108
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration that gives maximal stimulation of cyclic AMP production over the concentration range tested.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis, resolution, absolute stereochemistry, and enantioselectivity of 3',4'-dihydroxynomifensine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.58 | 5.73 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1788237 | — | — | 1 | 5.73 |
| CHEMBL119555 | — | — | 1 | 5.54 |
| CHEMBL59 | DOPAMINE | 4.0 | 1 | 5.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1788237 | — | EC50 | = | 1870.0 | nM | 5.73 |
| CHEMBL119555 | — | EC50 | = | 2880.0 | nM | 5.54 |
| CHEMBL59 | DOPAMINE | EC50 | = | 3500.0 | nM | 5.46 |