Assay Detail
Functional
CHEMBL824422
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of estradiol-stimulated ZR-75-1-cell proliferation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | ZR-75-1 |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
(S)-(+)-4-[7-(2,2-dimethyl-1-oxopropoxy)-4-methyl-2-[4-[2-(1-piperidinyl)-ethoxy]phenyl]-2H-1-benzopyran-3-yl]-phenyl 2,2-dimethylpropanoate (EM-800): a highly potent, specific, and orally active nonsteroidal antiestrogen.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.26 | 9.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL68055 | ACOLBIFENE | 3.0 | 1 | 9.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL68055 | ACOLBIFENE | IC50 | = | 0.55 | nM | 9.26 |