Assay Detail
Functional
CHEMBL824501
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for ability to stimulate metabotropic glutamate receptor (mGluR) mediated phosphoinositide hydrolysis in rat hippocampus
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Hippocampus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Metabotropic glutamate receptor (CHEMBL2111335) ↗| Type | PROTEIN FAMILY |
| Organism | Rattus norvegicus |
Publication
Enzymatic resolution and pharmacological activity of the enantiomers of 3,5-dihydroxyphenylglycine, a metabotropic glutamate receptor agonist
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 4.96 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL39221 | — | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL39221 | — | EC50 | = | 10900.0 | nM | 4.96 |