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Assay Detail

CHEMBL824630

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Signal transduction efficacy in cAMP assay in CHO cells expressing human melanocortin receptor 5
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type CHO
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Melanocortin receptor 5 (CHEMBL4608)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Selective, high affinity peptide antagonists of alpha-melanotropin action at human melanocortin receptor 4: their synthesis and biological evaluation in vitro.
Bednarek MA, MacNeil T, Kalyani RN, Tang R, Van der Ploeg LH, Weinberg DH.
J Med Chem (2001) 44 : 3665 -3672
PubMed 11606131 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 9.92 9.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL442504 1 9.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL442504 EC50 = 0.12 nM 9.92